Published in
American Association for the Advancement of Science, Science Translational Medicine, 499(11), 2019
DOI: 10.1126/scitranslmed.aav4634
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CFTR-PTEN–dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection
Journal article published in 2019 by
Sebastián A. Riquelme 
,
Carmen Lozano ,
Ahmed M. Moustafa ,
Kalle Liimatta ,
Kira L. Tomlinson ,
Clemente Britto ,
Sara Khanal ,
Simren K. Gill,
Apurva Narechania,
Jose M. Azcona-Gutiérrez ,
Emily DiMango,
Yolanda Saénz ,
Paul Planet ,
Alice Prince
,
Carmen Lozano ,
Ahmed M. Moustafa ,
Kalle Liimatta ,
Kira L. Tomlinson ,
Clemente Britto ,
Sara Khanal ,
Simren K. Gill,
Apurva Narechania,
Jose M. Azcona-Gutiérrez ,
Emily DiMango,
Yolanda Saénz ,
Paul Planet ,
Alice Prince
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Abstract
Excess succinate due to CFTR-PTEN dysfunction selects for Pseudomonas aeruginosa mutants adapted to the airway.