Published in
American Association for the Advancement of Science, Science Signaling, 582(12), 2019
DOI: 10.1126/scisignal.aav3048
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mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β <sub>1</sub> –induced collagen biosynthesis
Journal article published in 2019 by
Brintha Selvarajah 
,
Ilan Azuelos ,
Manuela Platé ,
Delphine Guillotin,
Ellen J. Forty,
Greg Contento,
Hannah V. Woodcock ,
Matthew Redding,
Adam Taylor,
Gino Brunori,
Pascal F. Durrenberger,
Riccardo Ronzoni ,
Andy D. Blanchard ,
Paul F. Mercer,
Dimitrios Anastasiou
and other authors.
,
Ilan Azuelos ,
Manuela Platé ,
Delphine Guillotin,
Ellen J. Forty,
Greg Contento,
Hannah V. Woodcock ,
Matthew Redding,
Adam Taylor,
Gino Brunori,
Pascal F. Durrenberger,
Riccardo Ronzoni ,
Andy D. Blanchard ,
Paul F. Mercer,
Dimitrios Anastasiou
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Through mTORC1 signaling, TGF-β 1 stimulates glycine synthesis from glucose to support collagen production in lung fibroblasts.