Published in
American Association for the Advancement of Science, Science Immunology, 42(4), 2019
DOI: 10.1126/sciimmunol.aax8189
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GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment
Journal article published in 2019 by
Marie Jo Halaby 
,
Kebria Hezaveh ,
Sara Lamorte,
M. Teresa Ciudad,
Andreas Kloetgen,
Bethany L. MacLeod,
Mengdi Guo,
Ankur Chakravarthy ,
Tiago Da Silva Medina ,
Stefano Ugel ,
Aristotelis Tsirigos ,
Vincenzo Bronte ,
David H. Munn ,
Trevor J. Pugh ,
Daniel D. De Carvalho
and other authors.
,
Kebria Hezaveh ,
Sara Lamorte,
M. Teresa Ciudad,
Andreas Kloetgen,
Bethany L. MacLeod,
Mengdi Guo,
Ankur Chakravarthy ,
Tiago Da Silva Medina ,
Stefano Ugel ,
Aristotelis Tsirigos ,
Vincenzo Bronte ,
David H. Munn ,
Trevor J. Pugh ,
Daniel D. De Carvalho
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
GCN2 is a key driver of Mϕ and MDSC polarization in the tumor microenvironment causing T cell exhaustion.