Published in
American Association for the Advancement of Science, Science Signaling, 601(12), 2019
DOI: 10.1126/scisignal.aar3993
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LGP2 binds to PACT to regulate RIG-I– and MDA5-mediated antiviral responses
Journal article published in 2019 by
Raul Y. Sanchez David 
,
Chantal Combredet ,
Valérie Najburg,
Gael A. Millot ,
Guillaume Beauclair ,
Benno Schwikowski ,
Thibaut Léger ,
Jean-Michel Camadro ,
Yves Jacob ,
Jacques Bellalou ,
Nolwenn Jouvenet ,
Frédéric Tangy ,
Anastassia V. Komarova
,
Chantal Combredet ,
Valérie Najburg,
Gael A. Millot ,
Guillaume Beauclair ,
Benno Schwikowski ,
Thibaut Léger ,
Jean-Michel Camadro ,
Yves Jacob ,
Jacques Bellalou ,
Nolwenn Jouvenet ,
Frédéric Tangy ,
Anastassia V. Komarova
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Abstract
The interaction between LGP2 and a component of the RNA-silencing machinery enables coordination of innate immune responses.