Published in
American Association for the Advancement of Science, Science Translational Medicine, 510(11), 2019
DOI: 10.1126/scitranslmed.aas9917
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Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in Plasmodium falciparum
Journal article published in 2019 by
Joost Schalkwijk 
,
Erik L. Allman ,
Patrick A. M. Jansen ,
Laura E. de Vries ,
Julie M. J. Verhoef ,
Suzanne Jackowski,
Peter N. M. Botman,
Christien A. Beuckens-Schortinghuis ,
Karin M. J. Koolen ,
Judith M. Bolscher ,
Martijn W. Vos,
Karen Miller,
Stacy A. Reeves ,
Helmi Pett,
Graham Trevitt
and other authors.
,
Erik L. Allman ,
Patrick A. M. Jansen ,
Laura E. de Vries ,
Julie M. J. Verhoef ,
Suzanne Jackowski,
Peter N. M. Botman,
Christien A. Beuckens-Schortinghuis ,
Karin M. J. Koolen ,
Judith M. Bolscher ,
Martijn W. Vos,
Karen Miller,
Stacy A. Reeves ,
Helmi Pett,
Graham Trevitt
and other authors.
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Abstract
Pantothenamides form antimetabolites that interfere with acetyl-CoA metabolism in the human malaria parasite Plasmodium falciparum.