Published in
American Association for the Advancement of Science, Science Translational Medicine, 486(11), 2019
DOI: 10.1126/scitranslmed.aar6659
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Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development
Journal article published in 2019 by
Donghyun Kang 
,
Jungkwon Shin ,
Yongsik Cho,
Hyeon-Seop Kim,
Young-Ran Gu,
Haedong Kim ,
Kwon Tae You,
Moon Jong Chang,
Chong Bum Chang ,
Seung-Baik Kang,
Jong-Seo Kim ,
V. Narry Kim ,
Jin-Hong Kim
,
Jungkwon Shin ,
Yongsik Cho,
Hyeon-Seop Kim,
Young-Ran Gu,
Haedong Kim ,
Kwon Tae You,
Moon Jong Chang,
Chong Bum Chang ,
Seung-Baik Kang,
Jong-Seo Kim ,
V. Narry Kim ,
Jin-Hong Kim
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Abstract
Senescence-induced miR-204 alters the proteoglycan biosynthesis pathway and disrupts matrix homeostasis in osteoarthritic cartilage.