Published in
American Association for the Advancement of Science, Science Immunology, 30(3), 2018
DOI: 10.1126/sciimmunol.aau8714
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Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant
Journal article published in 2018 by
Stéphanie Boisson-Dupuis 
,
Noe Ramirez-Alejo ,
Zhi Li ,
Etienne Patin ,
Geetha Rao,
Gaspard Kerner ,
Che Kang Lim,
Dimitry N. Krementsov ,
Nicholas Hernandez,
Cindy S. Ma ,
Qian Zhang ,
Janet Markle ,
Ruben Martinez-Barricarte,
Kathryn Payne ,
Robert Fisch
and other authors.
,
Noe Ramirez-Alejo ,
Zhi Li ,
Etienne Patin ,
Geetha Rao,
Gaspard Kerner ,
Che Kang Lim,
Dimitry N. Krementsov ,
Nicholas Hernandez,
Cindy S. Ma ,
Qian Zhang ,
Janet Markle ,
Ruben Martinez-Barricarte,
Kathryn Payne ,
Robert Fisch
and other authors.
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Abstract
Homozygosity for the P1104A missense variant of the TYK2 Janus kinase is common monogenic etiology of primary tuberculosis.