The objective of this study was to evaluate the productive potential and mineral composition of the forage cactus IPA-Sertânia (Nopalea cochenillifera Salm Dyck). This species was analyzed both in monoculture and intercropped with leucaena [Leucaena leucocephala (Lam.) De Wit.] and gliricidia [Gliricidia sepium (Jacq. Steud.], and was assessed with different sources of manure (cattle, sheep, goat, and broiler litter) serving as fertilizer. The experiment was conducted at the Experimental Station of the Instituto Agronômico de Pernambuco in Caruaru, PE, Brazil. Treatments were allocated in a split-plot arrangement in a randomized complete block design, with four replications. Main plots consisted of cropping systems, while the split-plots were dedicated to manure sources. Cactus harvest was carried out after two years of regrowth. Response variables included both production and nitrogen (N), phosphorus (P), potassium (K), calcium (Ca), and magnesium (Mg) concentrations. No differences were observed for cactus production between the cropping systems, with an average value of 22.1Mg dry matter ha-1 2 years-1. In the intercropped systems, greater proximity to the legumes increased the production of the cactus in the treatments with the cattle and sheep manure, and increased the concentrations of P, K, and Mg, but not of N. The introduction of tree legumes, along with the application of manure, contributes to an increase in production and nutrient concentration of IPA-Sertânia cactus.