Published in

Public Library of Science, PLoS ONE, 4(4), p. e5035, 2009

DOI: 10.1371/journal.pone.0005035

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Tracking Membrane Protein Association in Model Membranes

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Membrane proteins are essential in the exchange processes of cells. In spite of great breakthrough in soluble proteins studies, membrane proteins structures, functions and interactions are still a challenge because of the difficulties related to their hydrophobic properties. Most of the experiments are performed with detergent-solubilized membrane proteins. However widely used micellar systems are far from the biological two-dimensions membrane. The development of new biomimetic membrane systems is fundamental to tackle this issue.