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Royal Society of Chemistry, RSC Advances, 5(10), p. 2856-2869, 2020

DOI: 10.1039/c9ra09523c

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Protein corona formation moderates the release kinetics of ion channel antagonists from transferrin-functionalized polymeric nanoparticles

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Transferrin (Tf)-functionalized p(HEMA-ran-GMA) nanoparticles were designed to incorporate and release a water-soluble combination of three ion channel antagonists, identified as a promising therapy for secondary degeneration following neurotrauma.