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American Society for Microbiology, Journal of Clinical Microbiology, 7(51), p. 2388-2390, 2013

DOI: 10.1128/jcm.00640-13

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Klebsiella pneumoniae Carbapenemase-Producing Enterobacteriaceae Testing Susceptible to Cefepime by Reference Methods

Journal article published in 2013 by Renata C. Picão, Ronald N. Jones, Rodrigo E. Mendes ORCID, Mariana Castanheira
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT β-Lactam susceptibility of 499 Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae , determined by reference broth microdilution, demonstrated that 14.4% of isolates were categorized as cefepime susceptible according to current CLSI breakpoints. Ceftazidime- and meropenem-susceptible isolates were also observed (2.6 and 3.0%, respectively). Cefepime-susceptible KPC-producing isolates may confuse laboratory staff and clinicians in their therapeutic choices.