Published in
American Association for the Advancement of Science, Science Translational Medicine, 473(11), 2019
DOI: 10.1126/scitranslmed.aau3174
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Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay
Journal article published in 2019 by
Jerzy M. Dziekan 
,
Han Yu ,
Dan Chen ,
Lingyun Dai ,
Grennady Wirjanata,
Andreas Larsson ,
Nayana Prabhu ,
Radoslaw M. Sobota ,
Zbynek Bozdech ,
Pär Nordlund
,
Han Yu ,
Dan Chen ,
Lingyun Dai ,
Grennady Wirjanata,
Andreas Larsson ,
Nayana Prabhu ,
Radoslaw M. Sobota ,
Zbynek Bozdech ,
Pär Nordlund
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Abstract
A cellular thermal shift assay (CETSA) protocol identifies and resolves antimalarial drug targets in P. falciparum .