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Canadian Science Publishing, Canadian Journal of Microbiology, 8(65), p. 623-628, 2019

DOI: 10.1139/cjm-2019-0048

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Oxidative stress resistance and fitness-compensatory response in vancomycin-intermediate Staphylococcus aureus (VISA)

Journal article published in 2019 by Xin-Ee Tan, Hui-Min Neoh, Longzhu Cui ORCID, Keiichi Hiramatsu, Rahman Jamal
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

In this study, vancomycin-intermediate Staphylococcus aureus (VISA) cells carrying vraS and (or) graR mutations were shown to be more resistant to oxidative stress. Caenorhabditis elegans infected with these strains in turn demonstrated lower survival. Altered regulation in oxidative stress response and virulence appear to be physiological adaptations associated with the VISA phenotype in the Mu50 lineage.