Experimental mechano-stimulation of biologic samples serves to understand fundamental processes in mechano biology. Unfortunately, present techniques do not allow contact-free investigation of material characteristics . We developed a mechano-stimulator that functions under the assumption that the counterforce generated by a biologic sample placed on a carrier membrane is extractable from the total signal. As material characteristics of biologic samples are poorly defined, we substituted them by polyurethane and latex membranes. We hypothesized that knowing the carrier membranes' compliance allows calculation of the sample's compliance. Compliances and mean errors of compliance measurements of latex membranes were larger than those of polyurethane ones (p0.05). The variability of compliance values was serveral fold larger (p