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Royal Society of Chemistry, RSC Advances, 1(10), p. 451-460, 2020

DOI: 10.1039/c9ra05878h

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Seven new metabolites of drostanolone heptanoate by using Beauveria bassiana, and Macrophomina phaseolina cell suspension cultures

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Incubation of drostanolone heptanoate (1) with B. bassiana and M. phaseolina afforded seven new and two known metabolites.The main sites of hydroxylation include C-5, C-7, C-11, C-14, C-15, and C-20, hydrolysis at C-17, and reduction at C-3 of 1.