Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor–tissue factor axis
Journal article published in 2019 by
Mostafa Belghasem 
,
Daniel Roth,
Sean Richards,
Marc Arthur Napolene,
Joshua Walker,
Wenqing Yin,
Nkiruka Arinze,
Chimera Lyle,
Cheryl Spencer,
Jean M. Francis,
Cristal Thompson,
Christopher Andry,
Stephen A. Whelan ,
Norman Lee,
Katya Ravid
and other authors.
,
Daniel Roth,
Sean Richards,
Marc Arthur Napolene,
Joshua Walker,
Wenqing Yin,
Nkiruka Arinze,
Chimera Lyle,
Cheryl Spencer,
Jean M. Francis,
Cristal Thompson,
Christopher Andry,
Stephen A. Whelan ,
Norman Lee,
Katya Ravid
and other authors.
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Abstract
Currently, we have insufficient understanding of venous thromboembolism in cancer patients. In this article, the authors reveal a novel mechanism for colon cancer-associated venous thrombosis using a murine model.