Elsevier, Journal of Pediatrics, 6(156), p. 889-895
DOI: 10.1016/j.jpeds.2010.01.017
Full text: Unavailable
OBJECTIVE: To determine whether preterm birth influences functional neuronal development in adulthood. STUDY DESIGN: We evaluated adults born very preterm (VPT; control participants) was positively associated with gray matter volume in the left parahippocampal gyrus, with VPT participants with the youngest gestational age (eg, born 28 weeks or less) having both increased gray matter and functional activation in this region. These results may reflect the process of neural reorganization after early brain injury. CONCLUSION: Preterm birth leads to functional neuronal differences in adulthood, which are meditated by both structural variations in task-specific regions, and gestational age.