Published in
Oxford University Press (OUP), Brain, 12(142), p. 3771-3790, 2019
DOI: 10.1093/brain/awz302
Links
Tools
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis
Journal article published in 2019 by
Scott P. Allen 
,
Benjamin Hall,
Ryan Woof,
Laura Francis,
Noemi Gatto ,
Allan C. Shaw,
Monika Myszczynska,
Jordan Hemingway,
Ian Coldicott,
Amelia Willcock,
Lucy Job,
Rachel M. Hughes,
Camilla Boschian,
Nadhim Bayatti,
Paul R. Heath
and other authors.
,
Benjamin Hall,
Ryan Woof,
Laura Francis,
Noemi Gatto ,
Allan C. Shaw,
Monika Myszczynska,
Jordan Hemingway,
Ian Coldicott,
Amelia Willcock,
Lucy Job,
Rachel M. Hughes,
Camilla Boschian,
Nadhim Bayatti,
Paul R. Heath
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
Published version:
archiving forbidden
Data provided by 
Abstract
Energy metabolism is altered in amyotrophic lateral sclerosis and its animal models. Using metabolic profiling, Allen et al. reveal a loss of metabolic flexibility in induced astrocytes derived from patients with C9orf72 ALS, caused by defects in glycogen, fructose and mitochondrial energy substrate transport.