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American Society of Hematology, Blood Advances, 23(3), p. 4117-4130, 2019

DOI: 10.1182/bloodadvances.2019000835

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A novel immature natural killer cell subpopulation predicts relapse after cord blood transplantation

Journal article published in 2019 by Li Li, Han Chen, David Marin, Yuanxin Xi, Qi Miao, Jiangxing Lv, Pinaki Prosad Banerjee, Hila Shaim, May Daher, Rafet Basar, Nobuhiko Imahashi, Juan Jimenez, Bingqian Hu, Rohtesh S. Mehta, Lucila Nassif Kerbauy and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points Cytomegalovirus reactivation and interleukin 15 are major contributors to NK cell repertoire diversity and maturation after CBT. An immature NK cell subset characterized by low diversity index and poor effector function was highly predictive of relapse after CBT.