HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations.
Journal article published in 1999 by
A. Spurkland,
S. Saarinen,
Km M. Boberg,
S. Mitchell,
U. Broome,
L. Caballeria,
E. Ciusani,
R. Chapman,
G. Ercilla,
O. Fausa,
I. Knutsen,
A. Pares 
,
F. Rosina,
O. Olerup,
E. Thorsby
and other authors.
,
F. Rosina,
O. Olerup,
E. Thorsby
and other authors.
Abstract
The association of primary sclerosing cholangitis (PSC) to HLA class II genes was studied by comparing patients from five different European populations. Deduced HLA-DRB1, DQA1, DQB1 haplotypes of 256 PSC patients from England, Italy, Norway, Spain and Sweden were compared to those observed in 764 ethnically-matched controls. Increased frequencies of the DRB1*03, DQA1*0501, DQB1*02 (RR=3.0, P