Published in
American Society of Hematology, Blood Advances, 23(3), p. 3968-3972, 2019
DOI: 10.1182/bloodadvances.2019000181
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Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma
Journal article published in 2019 by
David A. Alagpulinsa 
,
Subodh Kumar,
Srikanth Talluri,
Purushothama Nanjappa,
Leutz Buon,
Chandraditya Chakraborty,
Mehmet K. Samur,
Raphael Szalat ,
Masood A. Shammas ,
Nikhil C. Munshi
,
Subodh Kumar,
Srikanth Talluri,
Purushothama Nanjappa,
Leutz Buon,
Chandraditya Chakraborty,
Mehmet K. Samur,
Raphael Szalat ,
Masood A. Shammas ,
Nikhil C. Munshi
This paper is made freely available by the publisher.
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Abstract
Key Points UBE2T is frequently amplified and/or overexpressed and is required for homologous recombination activity in multiple myeloma cells. UBE2T is a potential therapeutic target to increase chemosensitivity in multiple myeloma cells.