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American Society of Hematology, Blood, 23(134), p. 2046-2058, 2019

DOI: 10.1182/blood.2019000381

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MELK mediates the stability of EZH2 through site-specific phosphorylation in extranodal natural killer/T-cell lymphoma

This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Data provided by SHERPA/RoMEO

Abstract

This article describes the interplay between the serine/threonine kinase maternal embryonic leucine zipper kinase (MELK) and the enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2) and provides a basis for targeting this enzymatic pathway in mature natural killer/T-cell malignancies.