Smell tests can be useful in the differential diagnosis of Parkinson's disease (PD) but are affected by cultural factors. Currently there is no smell test tailored for the Mexican population but the brief smell identification test (B-SIT) was created as a cross-cultural SIT. We have created a translation of this test into Spanish adapted to the Mexican population and have applied it to 70 PD patients and 70 age- and gender-matched controls. The B-SIT differentiated PD and controls with 71.4% sensitivity and 85.7% specificity, when subjects were divided into two age groups. © 2010 Movement Disorder Society.