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Oxford University Press (OUP), Journal of Antimicrobial Chemotherapy, 1(70), p. 273-278

DOI: 10.1093/jac/dku338

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Bacteraemia incidence, causative organisms and resistance patterns, antibiotic strategies and outcomes in a single university hospital ICU: continuing improvement between 2000 and 2013.

Journal article published in 2014 by Vincenzo De Santis, De Santis, Mihaela Gresoiu, Alberto Corona, Ap Peter R. Wilson, Mervyn Singer ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The optimal duration of antibiotic treatment in patients with bloodstream infections remains contentious, with concerns regarding both undertreatment and the encouragement of antibiotic resistance. In our ICU we traditionally use short-course antibiotic monotherapy as the mainstay of treatment. We sought to document the impact of this strategy on pathogen type, resistance patterns and patient outcomes. A comparison was made against data collected during a similar exercise in 2000.