Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 12(63), 2019
DOI: 10.1128/aac.01067-19
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No Evidence of Plasmodium falciparum k13 Artemisinin Resistance-Conferring Mutations over a 24-Year Analysis in Coastal Kenya but a Near Complete Reversion to Chloroquine-Sensitive Parasites
Journal article published in 2019 by
Kevin Wamae 
,
Dorcas Okanda,
Leonard Ndwiga,
Victor Osoti,
Kelvin M. Kimenyi ,
Abdirahman I. Abdi,
Philip Bejon,
Colin Sutherland,
Lynette Isabella Ochola-Oyier
,
Dorcas Okanda,
Leonard Ndwiga,
Victor Osoti,
Kelvin M. Kimenyi ,
Abdirahman I. Abdi,
Philip Bejon,
Colin Sutherland,
Lynette Isabella Ochola-Oyier
This paper is made freely available by the publisher.
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Abstract
Antimalarial drug resistance is a substantial impediment to malaria control. The spread of resistance has been described using genetic markers, which are important epidemiological tools. We carried out a temporal analysis of changes in allele frequencies of 12 drug resistance markers over 2 decades of changing antimalarial drug policy in Kenya.