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American Society of Hematology, Blood Advances, 21(3), p. 3322-3332, 2019

DOI: 10.1182/bloodadvances.2019000328

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Blast phenotype and comutations in acute myeloid leukemia with mutated NPM1 influence disease biology and outcome

Journal article published in 2019 by Emily F. Mason ORCID, Robert P. Hasserjian, Nidhi Aggarwal ORCID, Adam C. Seegmiller, Olga Pozdnyakova ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points Blast phenotype is an independent predictor of outcome in NPM1-mutated AML. Patients with a DN blast phenotype (lacking CD34 and HLA-DR expression) harbor TET2/IDH mutations and show superior outcomes.