American Society of Hematology, Blood Advances, 21(3), p. 3201-3213, 2019
DOI: 10.1182/bloodadvances.2019000641
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Key Points DNA replication timing of >100 pediatric leukemic samples identified BCP-ALL subtype-specific genome alteration signatures. Comparative analyses identified features of specific stages of B-cell differentiation and potential associations with clinical outcome.