CD137 deficiency causes immune dysregulation with predisposition to lymphomagenesis
Journal article published in 2019 by
Ido Somekh,
Marini Thian 
,
David Medgyesi,
Nesrin Gülez,
Thomas Magg,
Alejandro Gallón Duque,
Tali Stauber,
Atar Lev,
Ferah Genel,
Ekrem Unal ,
Amos J. Simon,
Yu Nee Lee,
Artem Kalinichenko ,
Jasmin Dmytrus,
Michael J. Kraakman
and other authors.
,
David Medgyesi,
Nesrin Gülez,
Thomas Magg,
Alejandro Gallón Duque,
Tali Stauber,
Atar Lev,
Ferah Genel,
Ekrem Unal ,
Amos J. Simon,
Yu Nee Lee,
Artem Kalinichenko ,
Jasmin Dmytrus,
Michael J. Kraakman
and other authors.
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Abstract
Somekh and colleagues identify CD137, a member of the tumor necrosis factor superfamily, as a novel cause of immunodeficiency associated with a risk of autoimmunity and lymphoid malignancy.