Published in
American Society for Microbiology, Infection and Immunity, 12(87), 2019
DOI: 10.1128/iai.00692-19
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Lipopolysaccharides from Different Burkholderia Species with Different Lipid A Structures Induce Toll-Like Receptor 4 Activation and React with Melioidosis Patient Sera
Journal article published in 2019 by
Sineenart Sengyee,
Sung Hwan Yoon 
,
T. Eoin West,
Robert K. Ernst ,
Narisara Chantratita
,
T. Eoin West,
Robert K. Ernst ,
Narisara Chantratita
This paper is made freely available by the publisher.
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Abstract
Lipopolysaccharides (LPSs) of Gram-negative bacteria comprise lipid A, core, and O-polysaccharide (OPS) components. Studies have demonstrated that LPSs isolated from the pathogenic species Burkholderia pseudomallei and Burkholderia mallei and from less-pathogenic species, such as Burkholderia thailandensis , are potent immune stimulators.