Dissemin is shutting down on January 1st, 2025

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Russian Journal of Biotherapy, 4(17), p. 20-26, 2019

DOI: 10.17650/1726-9784-2018-17-4-20-26

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Indolocarbazole derivatives – a promising class of anticancer drugs

Journal article published in 2019 by M. P. Kiseleva, V. S. Pokrovsky ORCID, V. V. Tataskiy, L. M. Borisova, I. S. Golubeva, L. V. Ektova
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Abstract

The paper discusses the possible mechanisms of antitumor action of indolocarbazole derivatives. Here we present a data that show interaction drugs based on indolocarbazole derivatives with several intracellular targets and consequently activation different pathways of cell death. Also we present results of our studies on the mechanisms of antitumor action of compounds LCS-1006 and LCS-1208 synthesized in the N.N. Blokhin Russian Cancer Research Center, Ministry of Health of Russia.