Dissemin is shutting down on January 1st, 2025

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Open Access Publishing London, Head and Neck Oncology, 1(3), 2011

DOI: 10.1186/1758-3284-3-7

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At the frontiers of surgery: review

Journal article published in 2011 by Tahwinder Upile, Waseem K. Jerjes, Henricus J. Sterenborg, Brian J. Wong, Adel K. El-Naggar, Justus F. Ilgner, Ann Sandison, Max J. Witjes ORCID, Merrill A. Biel, Robert van Veen, Zaid Hamdoon, Ann Gillenwater, Charles A. Mosse, Dominic J. Robinson, Christian S. Betz and other authors.
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract The complete surgical removal of disease is a desirable outcome particularly in oncology. Unfortunately much disease is microscopic and difficult to detect causing a liability to recurrence and worsened overall prognosis with attendant costs in terms of morbidity and mortality. It is hoped that by advances in optical diagnostic technology we could better define our surgical margin and so increase the rate of truly negative margins on the one hand and on the other hand to take out only the necessary amount of tissue and leave more unaffected non-diseased areas so preserving function of vital structures. The task has not been easy but progress is being made as exemplified by the presentations at the 2nd Scientific Meeting of the Head and Neck Optical Diagnostics Society (HNODS) in San Francisco in January 2010. We review the salient advances in the field and propose further directions of investigation.