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Oxford University Press (OUP), Clinical Infectious Diseases, 11(69), p. 2022-2025, 2019

DOI: 10.1093/cid/ciz250

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Kaposi Sarcoma Herpesvirus Inflammatory Cytokine Syndrome–like Clinical Presentation in Human Immunodeficiency Virus–infected Children in Malawi

Journal article published in 2019 by Nader Kim El-Mallawany, William Kamiyango, Jimmy Villiera, Erin C. Peckham-Gregory, Michael E. Scheurer, Casey L. McAtee, Carl E. Allen, Carrie L. Kovarik, Dale Frank, Anthony B. Eason ORCID, Carolina Caro-Vegas, Elizabeth Y. Chiao, Gordon E. Schutze, Nmazuo W. Ozuah, Parth S. Mehta and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Abstract We describe 7 human immunodeficiency virus–infected Malawian children with Kaposi sarcoma who met criteria for Kaposi sarcoma herpesvirus (KSHV) inflammatory cytokine syndrome. Each presented with persistent fevers, bulky lymphadenopathy, massive hepatosplenomegaly, and severe cytopenias. Plasma analyses were performed in 2 patients, both demonstrating extreme elevations of KSHV viral load and interleukin 6.