Published in
Oxford University Press, Open Forum Infectious Diseases, 11(5), 2018
DOI: 10.1093/ofid/ofy275
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Tenofovir Alafenamide in Multimorbid HIV-Infected Patients With Prior Tenofovir-Associated Renal Toxicity
Journal article published in 2018 by
Laura N. Walti,
Julia Steinrücken,
Andri Rauch 
,
Gilles Wandeler
,
Gilles Wandeler
This paper is made freely available by the publisher.
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Abstract
AbstractAlthough the use of tenofovir alafenamide (TAF), a new prodrug of tenofovir, was safe and efficacious in clinical trials, real-world data from multimorbid individuals are scarce. Among 10 persons living with HIV with previous tenofovir disoproxil fumarate–induced nephrotoxicity, renal function remained stable, and proteinuria decreased in several patients after the switch to TAF.