Published in
Royal Society of Chemistry, Chemical Science, 42(10), p. 9663-9672, 2019
DOI: 10.1039/c9sc04242c
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Anion carriers as potential treatments for cystic fibrosis: transport in cystic fibrosis cells, and additivity to channel-targeting drugs
Journal article published in 2019 by
Hongyu Li 
,
Hennie Valkenier ,
Abigail G. Thorne,
Christopher M. Dias ,
James A. Cooper ,
Marion Kieffer ,
Nathalie Busschaert ,
Philip A. Gale ,
David N. Sheppard ,
Anthony P. Davis
,
Hennie Valkenier ,
Abigail G. Thorne,
Christopher M. Dias ,
James A. Cooper ,
Marion Kieffer ,
Nathalie Busschaert ,
Philip A. Gale ,
David N. Sheppard ,
Anthony P. Davis
This paper is made freely available by the publisher.
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Abstract
Synthetic anion transporters are active in cystic fibrosis cells, and are additive to clinically-approved drugs, suggesting new combination therapies for this lethal genetic condition.