Published in
Oxford University Press (OUP), Brain, 11(142), p. 3502-3513, 2019
DOI: 10.1093/brain/awz269
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Interictal epileptiform discharges shape large-scale intercortical communication
Journal article published in 2019 by
Prawesh Dahal,
Naureen Ghani,
Adeen Flinker 
,
Patricia Dugan ,
Daniel Friedman,
Werner Doyle,
Orrin Devinsky,
Dion Khodagholy,
Jennifer N. Gelinas
,
Patricia Dugan ,
Daniel Friedman,
Werner Doyle,
Orrin Devinsky,
Dion Khodagholy,
Jennifer N. Gelinas
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Abstract
Focal epilepsy is associated with large-scale brain dysfunction. Dahal et al. reveal that interictal epileptiform discharges modulate normal brain rhythms in regions beyond the epileptic network, potentially impairing processes that rely heavily upon intercortical communication, such as cognition and memory.