This study investigates the mangaba residue (Hancornia speciosa Gomes) and used as a substrate for the production of enzymes by semi-solid fermentation (SSF) using Aspergillus niger. The physical-chemical and bioactive attributes of mangaba bagasse and its extracts were addressed. Polyphenols concentrations of 564.1 ± 0.047 mg of gallic acid / g of oil and Total Antioxidant Activity - TCA of 95.46 ± 1.58 mg ascorbic acid / g ethanolic extract were found. In addition to the higher enzymatic production of lipase (50.11 ± 0.02 U / g) and pectinase (0.45 ± 0.01 U / g) through SSF. In general, in comparison with other similar residues and other works the results presented by the mangaba residue are relevant because it is an inexpensive raw material with potential added value to be exploited for the production of enzymes by fermentation in solid substrate using A Niger and extraction of antioxidant compounds.