Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 11(63), 2019
DOI: 10.1128/aac.00520-19
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Cholic Acid-Peptide Conjugates as Potent Antimicrobials against Interkingdom Polymicrobial Biofilms
Journal article published in 2019 by
Siddhi Gupta,
Jyoti Thakur,
Sanjay Pal,
Ragini Gupta,
Deepakkumar Mishra,
Sandeep Kumar 
,
Kavita Yadav,
Amandeep Saini,
Prabhu S. Yavvari,
Madhukar Vedantham,
Archana Singh,
Aasheesh Srivastava,
Rajendra Prasad,
Avinash Bajaj
,
Kavita Yadav,
Amandeep Saini,
Prabhu S. Yavvari,
Madhukar Vedantham,
Archana Singh,
Aasheesh Srivastava,
Rajendra Prasad,
Avinash Bajaj
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Interkingdom polymicrobial biofilms formed by Gram-positive Staphylococcus aureus and Candida albicans pose serious threats of chronic systemic infections due to the absence of any common therapeutic target for their elimination. Herein, we present the structure-activity relationship (SAR) of membrane-targeting cholic acid-peptide conjugates (CAPs) against Gram-positive bacterial and fungal strains.