Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 11(63), 2019
DOI: 10.1128/aac.00863-19
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Trichophyton rubrum Azole Resistance Mediated by a New ABC Transporter, TruMDR3
Journal article published in 2019 by
Michel Monod,
Marc Feuermann 
,
Karine Salamin,
Marina Fratti,
Maya Makino,
Mohamed Mahdi Alshahni,
Koichi Makimura,
Tsuyoshi Yamada
,
Karine Salamin,
Marina Fratti,
Maya Makino,
Mohamed Mahdi Alshahni,
Koichi Makimura,
Tsuyoshi Yamada
This paper is made freely available by the publisher.
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Abstract
The mechanisms of terbinafine resistance in a set of clinical isolates of Trichophyton rubrum have been studied recently. Of these isolates, TIMM20092 also showed reduced sensitivity to azoles. The azole resistance of TIMM20092 could be inhibited by milbemycin oxime, prompting us to examine the potential of T. rubrum to develop resistance through multidrug efflux transporters.