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The Company of Biologists, Development, 19(146), 2019

DOI: 10.1242/dev.177162

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Visualising three-dimensional genome organisation in two dimensions

Journal article published in 2019 by Elizabeth Ing-Simmons ORCID, Juan M. Vaquerizas ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Data provided by SHERPA/RoMEO

Abstract

ABSTRACT The three-dimensional organisation of the genome plays a crucial role in developmental gene regulation. In recent years, techniques to investigate this organisation have become more accessible to labs worldwide due to improvements in protocols and decreases in the cost of high-throughput sequencing. However, the resulting datasets are complex and can be challenging to analyse and interpret. Here, we provide a guide to visualisation approaches that can aid the interpretation of such datasets and the communication of biological results.