Published in
American Society for Microbiology, Journal of Virology, 18(93), 2019
DOI: 10.1128/jvi.00472-19
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Antiretroviral Therapy Administration in Healthy Rhesus Macaques Is Associated with Transient Shifts in Intestinal Bacterial Diversity and Modest Immunological Perturbations
Journal article published in 2019 by
Alexandra M. Ortiz 
,
Jacob K. Flynn,
Sarah R. DiNapoli,
Ornella Sortino,
Ivan Vujkovic-Cvijin ,
Yasmine Belkaid,
Irini Sereti,
Jason M. Brenchley
,
Jacob K. Flynn,
Sarah R. DiNapoli,
Ornella Sortino,
Ivan Vujkovic-Cvijin ,
Yasmine Belkaid,
Irini Sereti,
Jason M. Brenchley
This paper was not found in any repository, but could be made available legally by the author.
Full text: Unavailable
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Abstract
Dysbiosis of the fecal microbiome is a common feature observed in ARV-treated people living with HIV. The degree to which HIV infection itself causes this dysbiosis remains unclear. Here, we demonstrate that medications used to treat HIV infection can influence the composition of the GI tract immune responses and its microbiome in the nonhuman primate SIV model.