Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 10(63), 2019
DOI: 10.1128/aac.00441-19
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1 H -Benzo[ d ]Imidazole Derivatives Affect MmpL3 in Mycobacterium tuberculosis
Journal article published in 2019 by
Małgorzata Korycka-Machała,
Albertus Viljoen,
Jakub Pawełczyk,
Paulina Borówka,
Bożena Dziadek,
Katarzyna Gobis,
Anna Brzostek,
Malwina Kawka,
Mickael Blaise,
Dominik Strapagiel,
Laurent Kremer 
,
Jarosław Dziadek
,
Jarosław Dziadek
This paper is made freely available by the publisher.
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Abstract
1 H -benzo[ d ]imidazole derivatives exhibit antitubercular activity in vitro at a nanomolar range of concentrations and are not toxic to human cells, but their mode of action remains unknown. Here, we showed that these compounds are active against intracellular Mycobacterium tuberculosis .