IntroductionCases of rare movement disorders like Huntington’s disease (HD) are not easy to diagnose, especially when occurring sporadically, without documented family history. In HD patients, MRI scans commonly feature atrophy of the striatum and reduced volume of white matter. But if morphological findings remain unspecific, functional PET imaging could provide valuable information to further clarify diagnosis. We present a case report of a 56-year-old woman suffering from mild hypokinetic-rigid syndrome and depression, suspicious of Parkinson’s disease, who was referred to 18F-DOPA and 18F-FDG PET/MRI scans at our department.