Published in

American Society for Microbiology, Infection and Immunity, 10(87), 2019

DOI: 10.1128/iai.00224-19

Links

Tools

Export citation

Search in Google Scholar

Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum Erythrocyte Membrane Protein 1 Antigen Family Varies between Groups A, B, and C

Journal article published in 2019 by Rebecca W. Olsen, Gertrude Ecklu-Mensah, Anja Bengtsson ORCID, Michael F. Ofori, Kwadwo A. Kusi, Kwadwo A. Koram, Lars Hviid ORCID, Yvonne Adams, Anja T. R. Jensen ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important malaria virulence factor. The protein family can be divided into clinically relevant subfamilies. ICAM-1-binding group A PfEMP1 proteins also bind endothelial protein C receptor and have been associated with cerebral malaria in children. IgG to these PfEMP1 proteins is acquired later in life than that to group A PfEMP1 not binding ICAM-1.