Published in

Elsevier, Journal of Biological Chemistry, 10(290), p. 6293-6302, 2015

DOI: 10.1074/jbc.m114.594671

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New Insights on the Mechanism of Quinoline-based DNA Methyltransferase Inhibitors*

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Background: 4-Aminoquinoline SGI-1027 and analogs inhibit DNA methylation, which is deregulated in cancers.