Human beings share the same community in which the usage of energy by fossil fuels leads to deterioration in the environment, typically global warming. When the temperature rises to the critical point and triggers the continual melting of permafrost, it can wreak havoc on the life of animals and humans. Solutions could include optimizing existing devices, systems, and platforms, as well as utilizing green energy as a replacement of non-renewable energy. In this special issue “Artificial Intelligence for Smart and Sustainable Energy Systems and Applications”, eleven (11) papers, including one review article, have been published as examples of recent developments. Guest editors also highlight other hot topics beyond the coverage of the published articles.