Published in
American Association for the Advancement of Science, Science, 6104(338), p. 222-226, 2012
Links
- ORCID
- ORCID
- ORCID
- American Association for the Advancement of Science
- ORCID
- [www.ncbi.nlm.nih.gov] | PDF
- [repository.bilkent.edu.tr] | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [repository.bilkent.edu.tr] | PDF
- [repository.bilkent.edu.tr] | PDF
Tools
A High Coverage Genome Sequence From an Archaic Denisovan Individual
,
Marie-Theres Gansauge,
Heng Li,
Fernando Racimo,
Swapan Mallick,
Joshua G. Schraiber,
Flora Jay,
Kay Prüfer,
Cesare de Filippo,
Peter H. Sudmant ,
Can Alkan,
Qiaomei Fu,
Ron Do,
Nadin Rohland
and other authors.
Full text: Download
Abstract
Ancient Genomics The Denisovans were archaic humans closely related to Neandertals, whose populations overlapped with the ancestors of modern-day humans. Using a single-stranded library preparation method, Meyer et al. (p. 222 , published online 30 August) provide a detailed analysis of a high-quality Denisovan genome. The genomic sequence provides evidence for very low rates of heterozygosity in the Denisova, probably not because of recent inbreeding, but instead because of a small population size. The genome sequence also illuminates the relationships between humans and archaics, including Neandertals, and establishes a catalog of genetic changes within the human lineage.