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Oxford University Press (OUP), Bioinformatics, 10(25), p. 1264-1270

DOI: 10.1093/bioinformatics/btp149

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Using multi-data hidden Markov models trained on local neighborhoods of protein structure to predict residue–residue contacts

Journal article published in 2009 by Patrik Björkholm, Pawel Daniluk, Andriy Kryshtafovych, Krzysztof Fidelis, Robin Andersson ORCID, Torgeir R. Hvidsten
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Motivation:Correct prediction of residue–residue contacts in proteins that lack good templates with known structure would take ab initio protein structure prediction a large step forward. The lack of correct contacts, and in particular long-range contacts, is considered the main reason why these methods often fail.