This editorial delivers an introduction to the <em>Media and Communication </em>thematic issue on “Communicating on/with Minorities” around the world. This thematic issue presents a multidisciplinary look at the field of communicating on and with different members of minority groups who, based on gender, ethnicity, sexual orientation, or a background in migration, experience relative disadvantage and marginalization compared to the dominant social group. The contributors to this thematic issue present a variety of professional contexts (i.e., portrayals in journalistic content, in fiction and non-fiction audiovisual content, on social media platforms and in health care). Taken together, the contributions examine various theoretical angles, thereby adopting new research directions through the use of quantitative, qualitative or mixed methodologies.