Published in
American Diabetes Association, Diabetes, 1(68), p. 188-197, 2018
DOI: 10.2337/db18-0620
Diabetes – Nicht nur eine Typ-Frage – www.diabeteskongress.de, 2019
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Insulin-like growth factor binding protein 2 (IGFBP-2) and the risk of developing type 2 diabetes
Journal article published in 2018 by
Clemens Wittenbecher 
,
Meriem Ouni,
Olga Kuxhaus,
Markus Jähnert,
Pascal Gottmann,
Andrea Teichmann,
Karina Meidtner,
Jennifer Kriebel,
M. Jaehnert,
Harald Grallert,
Tobias Pischon ,
Heiner Boeing,
Matthias B. Schulze ,
Annette Schürmann
,
Meriem Ouni,
Olga Kuxhaus,
Markus Jähnert,
Pascal Gottmann,
Andrea Teichmann,
Karina Meidtner,
Jennifer Kriebel,
M. Jaehnert,
Harald Grallert,
Tobias Pischon ,
Heiner Boeing,
Matthias B. Schulze ,
Annette Schürmann
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Abstract
Recent studies suggest that insulin-like growth factor binding protein 2 (IGFBP-2) may protect against type 2 diabetes, but population-based human studies are scarce. We aimed to investigate the prospective association of circulating IGFBP-2 concentrations and of differential methylation in the IGFBP-2 gene with type 2 diabetes risk.