Published in
Royal Society of Chemistry, Chemical Science, 22(10), p. 5815-5820, 2019
DOI: 10.1039/c9sc00446g
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Leoligin-inspired synthetic lignans with selectivity for cell-type and bioactivity relevant for cardiovascular disease
Journal article published in 2019 by
Thomas Linder 
,
Rongxia Liu ,
Atanas G. Atanasov ,
Yuanfang Li ,
Sophie Geyrhofer,
Stefan Schwaiger ,
Hermann Stuppner ,
Michael Schnürch ,
Verena M. Dirsch ,
Marko D. Mihovilovic
,
Rongxia Liu ,
Atanas G. Atanasov ,
Yuanfang Li ,
Sophie Geyrhofer,
Stefan Schwaiger ,
Hermann Stuppner ,
Michael Schnürch ,
Verena M. Dirsch ,
Marko D. Mihovilovic
This paper is made freely available by the publisher.
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Abstract
The first total synthesis of the edelweiss constituent leoligin is reported, together with the first pharmacological evaluation of the parent compound and some of its analogs.